Article
Influence of lifestyle choices on risks of CYP1B1 polymorphisms for prostate cancer.
Journal of cellular and molecular medicine - 1 Oct 2018
Kato Taku, Hashimoto Yutaka, Wong Ryan K, Mitsui Yozo, Maekawa Shigekatsu, Chang Inik, Shahryari Varahram, Yamamura Soichiro, Majid Shahana, Saini Sharanjot, Tabatabai Z Laura, Dahiya Rajvir, Deguchi Takashi, Tanaka Yuichiro
Abstract excerpt
Cytochrome P450 1B1 (CYP1B1) converts xenobiotics to carcinogens and how lifestyle choices may interact with CYP1B1 polymorphisms and affect prostate cancer risk was assessed. Blood genomic DNA from a Caucasian population was analysed at polymorphic sites of the 5' untranslated region of CYP1B1 using TaqMan genotyping assays. Overall, drinker status and minor alleles at rs2551188, rs2567206 and rs10175368 were...
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