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Article

Studies on mRNA electroporation of immature and mature dendritic cells: effects on their immunogenic potential.

Molecular biotechnology - 1 Oct 2008

Met Ozcan, Eriksen Jens, Svane Inge Marie

Abstract excerpt

Previous studies have shown that mRNA-electroporated dendritic cells (DCs) are able to process and present tumor-associated antigens, leading to the activation of tumor-specific T cells in vitro and in vivo. However, the optimal maturation state of antigen loading and half-life of the mRNA-translated protein product and its immunogenic epitopes are significant parameters, which needs to be clarified in order to...

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Source

Identifiers

PMID: 18543130
DOI: 10.1007/s12033-008-9071-6

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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