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Article

Electrochemotherapy impacts the viability, functionality and phenotype of murine dendritic cells in voltage-dependent manner.

Bioelectrochemistry (Amsterdam, Netherlands) - 1 Aug 2026

Bendix Maura B, Baker Kevin J, Forde Patrick F, Houston Aileen, Brint Elizabeth

Abstract excerpt

Dendritic cells (DCs) are central to the initiation of anti-tumour immunity, yet the direct effects of electrochemotherapy (ECT) on DC biology remain poorly defined. We investigated how varying electric field strengths (800, 1000, and 1300 V/cm) modulate murine DC viability, phenotype, Toll-like receptor (TLR) expression and functional responses in vitro. ECT induced predominantly necrotic cell death in a...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 41762907
DOI: 10.1016/j.bioelechem.2026.109263

Genes

TLR4
TLR7
TLR9
CD80
TLR6
TLR8

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

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