Article
Targeting potassium channels: new advances in cardiovascular therapy.
Recent patents on cardiovascular drug discovery - 1 Jun 2008
Martínez-Mármol Ramón, Roura-Ferrer Meritxell, Felipe Antonio
Abstract excerpt
Potassium channels, which are essential to a wide range of physiological processes, are involved in many diseases. Thus, alterations in such important proteins due to congenital deficiencies or to undesirable side-effects of common medications might lead to dysfunctions. Heart is one of those tissues where potassium channels play a crucial role. The maintenance of cardiac action potential appears to be the...
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