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Article

Causes of oncogenic chromosomal translocation.

Trends in genetics : TIG - 1 Jan 2006

Aplan Peter D

Abstract excerpt

Non-random chromosomal translocations are frequently associated with a variety of cancers, particularly hematologic malignancies and childhood sarcomas. In addition to their diagnostic utility, chromosomal translocations are increasingly being used in the clinic to guide therapeutic decisions. However, the mechanisms that cause these translocations remain poorly understood. Illegitimate V(D)J recombination, class...

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Share to Cell Transformation, Neoplastic
Share to Chromosomes, Human
Share to DNA Repair

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Hematologic Neoplasms

Share to Immunoglobulin Class Switching

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Share to Recombination, Genetic

Share to Translocation, Genetic

Source

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Identifiers

PMID: 16257470
DOI: 10.1016/j.tig.2005.10.002
PMCID: PMC1762911

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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