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Article

A role for VICKZ proteins in the progression of colorectal carcinomas: regulating lamellipodia formation

26 Apr 2008

Abstract excerpt

VICKZ proteins are a highly conserved family of RNA binding proteins, implicated in RNA regulatory processes such as intracellular RNA localization, RNA stability, and translational control. During embryogenesis, VICKZ proteins are required for neural crest migration and in adults, the proteins are overexpressed primarily in different cancers. We hypothesized that VICKZ proteins may play a role in cancer cell...

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PMID: 18535985
DOI: 10.1002/path.2376

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