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Article

Markers of epithelial-to-mesenchymal transition reflect tumor biology according to patient age and Gleason score in prostate cancer.

PloS one - 1 Jan 2017

Jędroszka Dorota, Orzechowska Magdalena, Hamouz Raneem, Górniak Karolina, Bednarek Andrzej K

Abstract excerpt

INTRODUCTION: Prostate carcinoma (PRAD) is one of the most frequently diagnosed malignancies amongst men worldwide. It is well-known that androgen receptor (AR) plays a pivotal role in a vast majority of prostate tumors. However, recent evidence emerged stating that estrogen receptors (ERs) may also contribute to prostate tumor development. Moreover, progression and aggressiveness of prostate cancer may be...

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Share to Age Factors
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Gene Expression Regulation, Neoplastic

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Source

Open in PubMed Open full text

Identifiers

PMID: 29206234
DOI: 10.1371/journal.pone.0188842
PMCID: PMC5714348

Genes

ESR1
ESR2
CTNNB1
KRT18
KRT19
MMP3
MUC1
SNAI2
ZEB1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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