Model for mapping imprinted quantitative trait loci in an inbred F2 design.

doi:10.1016/j.ygeno.2005.11.021

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Article

Model for mapping imprinted quantitative trait loci in an inbred F2 design.

Genomics - 1 Apr 2006

Cui Yuehua, Lu Qing, Cheverud James M, Littell Ramon C, Wu Rongling

Abstract excerpt

The role of imprinting in shaping development has been ubiquitously observed in plants, animals, and humans. However, a statistical method that can detect and estimate the effects of imprinted quantitative trait loci (iQTL) over the genome has not been extensively developed. In this article, we propose a maximum likelihood approach for testing and estimating the imprinted effects of iQTL that contribute to...

Topics

Algorithms
Alleles
Animals
Chromosome Mapping
Computer Simulation
Crosses, Genetic
Female
Genetic Markers
Genome
Genomic Imprinting
Likelihood Functions
Male
Mice
Mice, Inbred Strains
Models, Genetic
Monte Carlo Method
Quantitative Trait Loci

Source

Open in PubMed

Identifiers

PMID: 16413163
DOI: 10.1016/j.ygeno.2005.11.021

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