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Article

A genome-wide scan for common genetic variants with a large influence on warfarin maintenance dose.

Blood - 15 Aug 2008

Cooper Gregory M, Johnson Julie A, Langaee Taimour Y, Feng Hua, Stanaway Ian B, Schwarz Ute I, Ritchie Marylyn D, Stein C Michael, Roden Dan M, Smith Joshua D, Veenstra David L, Rettie Allan E, Rieder Mark J

Abstract excerpt

Warfarin dosing is correlated with polymorphisms in vitamin K epoxide reductase complex 1 (VKORC1) and the cytochrome P450 2C9 (CYP2C9) genes. Recently, the FDA revised warfarin labeling to raise physician awareness about these genetic effects. Randomized clinical trials are underway to test gene...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 18535201
DOI: 10.1182/blood-2008-01-134247
PMCID: PMC2515139

Genes

VKORC1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-18535201-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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A genome-wide scan for common genetic variants with a large influence on warfarin maintenance dose.PMID 18535201Read ↗

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