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Article

The genomic analysis of erythrocyte microRNA expression in sickle cell diseases.

PloS one - 4 Jun 2008

Chen Shao-Yin, Wang Yulei, Telen Marilyn J, Chi Jen-Tsan

Abstract excerpt

BACKGROUND: Since mature erythrocytes are terminally differentiated cells without nuclei and organelles, it is commonly thought that they do not contain nucleic acids. In this study, we have re-examined this issue by analyzing the transcriptome of a purified population of human mature erythrocytes from individuals with normal hemoglobin (HbAA) and homozygous sickle cell disease (HbSS). METHODS AND FINDINGS: Using...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 18523662
DOI: 10.1371/journal.pone.0002360
PMCID: PMC2408759

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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