Article
Extracellular microvesicle microRNAs in children with sickle cell anaemia with divergent clinical phenotypes.
British journal of haematology - 1 Sept 2016
Khalyfa Abdelnaby, Khalyfa Ahamed A, Akbarpour Mahzad, Connes Phillippe, Romana Marc, Lapping-Carr Gabrielle, Zhang Chunling, Andrade Jorge, Gozal David
Abstract excerpt
Sickle cell anaemia (SCA) is the most frequent genetic haemoglobinopathy, which exhibits a highly variable clinical course characterized by hyper-coagulable and pro-inflammatory states, as well as endothelial dysfunction. Extracellular microvesicles are released into biological fluids and play a role in modifying the functional phenotype of target cells. We hypothesized that potential differences in...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
