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Article

Red Blood Cells as Potential Repositories of MicroRNAs in the Circulatory System

3 Jun 2020

Abstract excerpt

The amount of erythrocyte-derived microRNAs (miRNAs) represents the majority of miRNAs expressed in whole blood. miR-451, miR-144, and miR-486, which are abundant in red blood cells (RBCs), are involved in the process of erythropoiesis and disease occurrence. Moreover, erythrocyte-derived miRNAs have been reported to be potential biomarkers of specific diseases. However, the function and underlying mechanisms of...

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PMID: 32582273
DOI: 10.3389/fgene.2020.00442

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