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Article

The intermediate filament network in cultured human keratinocytes is remarkably extensible and resilient.

PloS one - 4 Jun 2008

Fudge Douglas, Russell David, Beriault Dan, Moore Whitney, Lane E Birgitte, Vogl A Wayne

Abstract excerpt

The prevailing model of the mechanical function of intermediate filaments in cells assumes that these 10 nm diameter filaments make up networks that behave as entropic gels, with individual intermediate filaments never experiencing direct loading in tension. However, recent work has shown that single intermediate filaments and bundles are remarkably extensible and elastic in vitro, and therefore well-suited to...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 18523546
DOI: 10.1371/journal.pone.0002327
PMCID: PMC2390850

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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