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Article

Genetic variants of miRNA sequences and non-small cell lung cancer survival.

The Journal of clinical investigation - 1 Jul 2008

Hu Zhibin, Chen Jiaping, Tian Tian, Zhou Xiaoyi, Gu Haiyong, Xu Lin, Zeng Yi, Miao Ruifen, Jin Guangfu, Ma Hongxia, Chen Yijiang, Shen Hongbing

Abstract excerpt

Recent evidence indicates that small noncoding RNA molecules known as microRNAs (miRNAs) can function as tumor suppressors and oncogenes. Mutation, misexpression, and altered mature miRNA processing are implicated in carcinogenesis and tumor progression. Because SNPs in pre-miRNAs could alter miRNA processing, expression, and/or binding to target mRNA, we conducted a systematic survey of common pre-miRNA SNPs and...

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Identifiers

PMID: 18521189
DOI: 10.1172/JCI34934
PMCID: PMC2402113

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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