Article
RNA editing regulates insect gamma-aminobutyric acid receptor function and insecticide sensitivity.
Neuroreport - 11 Jun 2008
Es-Salah Zeineb, Lapied Bruno, Le Goff Gaëlle, Hamon Alain
Abstract excerpt
A-to-I pre-mRNA editing by adenosine deaminase enzymes has been reported to enhance protein diversity in the nervous system. In Drosophila, the resistance to dieldrin (RDL) gamma-aminobutyric acid (GABA) receptor subunit displays an editing site (R122) that is close to the putative GABA-binding site. We assessed the functional effects of editing at this site by expressing homomeric RDL receptors in Xenopus...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
