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Article

A drug transporter for all ages? ABCB1 and the developmental pharmacogenetics of cyclosporine.

Pharmacogenomics - 1 Jun 2008

Hesselink Dennis A, van Schaik Ron H N, Nauta Jeroen, van Gelder Teun

Abstract excerpt

Evaluation of: Fanta S, Niemi M, Jönsson S et al.: Pharmacogenetics of cyclosporine in children suggests an age-dependent influence of ABCB1polymorphisms. Pharmacogenet. Genomics 18(2), 77-90 (2008). The clinical use of the immunosuppressive agent cyclosporine is complicated by its toxicity, narrow therapeutic window and highly variable pharmacokinetics between individuals. In adults, genetic polymorphisms in the...

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Share to ATP Binding Cassette Transporter, Subfamily B
Share to ATP Binding Cassette Transporter, Subfamily B, Member 1

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 18518855
DOI: 10.2217/14622416.9.6.783

Genes

ABCB1
ABCC2

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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A drug transporter for all ages? ABCB1 and the developmental pharmacogenetics of cyclosporine.PMID 18518855Read ↗

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