Article
Monozygotic twins reveal germline contribution to allelic expression differences.
American journal of human genetics - 1 Jun 2008
Cheung Vivian G, Bruzel Alan, Burdick Joshua T, Morley Michael, Devlin James L, Spielman Richard S
Abstract excerpt
Variation in the level of gene expression is a major determinant of a cell's function and characteristics. Common allelic variants of genes can be expressed at different levels and thus contribute to phenotypic diversity. We have measured allelic expression differences at heterozygous loci in monozygotic twins and in unrelated individuals. We show that the extent of differential allelic expression is highly...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
