Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Rheumatoid arthritis is a heterogeneous disease: Evidence for differences in the activation of the STAT‐1 pathway between rheumatoid tissues

1 Aug 2003

Abstract excerpt

OBJECTIVE: To generate a molecular description of synovial tissue from rheumatoid arthritis (RA) patients that would allow us to unravel novel aspects of pathogenesis and to identify different forms of disease. METHODS: We applied complementary DNA microarray analysis to profile gene expression, with a focus on immune-related genes, in affected joint tissues from RA patients and in tissues from osteoarthritis...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Bone Metabolism and Diseases
Share to Cytokine Signaling Pathways and Interactions
Share to Rheumatoid Arthritis Research and Therapies

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 12905466
DOI: 10.1002/art.11096

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Rheumatoid arthritis is a heterogeneous disease: Evidence for differences in the activation of the STAT‐1 pathway between rheumatoid tissuesPMID 12905466Read ↗

Distinctive gene expression signatures in rheumatoid arthritis synovial tissue fibroblast cells: correlates with disease activitySemantic proximity Read ↗

Molecular profile of peripheral blood mononuclear cells from patients with rheumatoid arthritis.Semantic proximity Read ↗

RNA-seq analysis of synovial fibroblasts brings new insights into rheumatoid arthritisSemantic proximity Read ↗

Synovial Gene Signatures Associated with the Development of Rheumatoid Arthritis in At Risk Individuals: a Prospective StudySemantic proximity Read ↗

Molecular signatures and new candidates to target the pathogenesis of rheumatoid arthritisSemantic proximity Read ↗

Heterogeneity of Synovial Molecular Patterns in Patients with ArthritisSemantic proximity Read ↗

Abnormal networks of immune response-related molecules in bone marrow cells from patients with rheumatoid arthritis as revealed by DNA microarray analysisSemantic proximity Read ↗

Fibroblast-like synoviocytes derived from patients with rheumatoid arthritis show the imprint of synovial tissue heterogeneity: evidence of a link between an increased myofibroblast-like phenotype and high-inflammation synovitis.Semantic proximity Read ↗

Joint-specific DNA methylation and transcriptome signatures in rheumatoid arthritis identify distinct pathogenic processesSemantic proximity Read ↗

Gene expression analysis of rheumatoid arthritis synovial lining regions by cDNA microarray combined with laser microdissection: up-regulation of inflammation-associated STAT1, IRF1, CXCL9, CXCL10, and CCL5Semantic proximity Read ↗

Clinical implications of synovial tissue phenotypes in rheumatoid arthritisSemantic proximity Read ↗

Synovial Transcriptome Profiling for Predicting Biological Treatment Response in Rheumatoid Arthritis: A Feasibility studySemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.