Article
Gene expression profiling of peripheral blood from patients with untreated new-onset systemic juvenile idiopathic arthritis reveals molecular heterogeneity that may predict macrophage activation syndrome.
Arthritis and rheumatism - 1 Nov 2007
Fall Ndate, Barnes Michael, Thornton Sherry, Luyrink Lorie, Olson Judyann, Ilowite Norman T, Gottlieb Beth S, Griffin Thomas, Sherry David D, Thompson Susan, Glass David N, Colbert Robert A, Grom Alexei A
Abstract excerpt
OBJECTIVE: Systemic juvenile idiopathic arthritis (JIA) is frequently associated with the development of macrophage activation syndrome. This study was undertaken to better understand the relationship between systemic JIA and macrophage activation syndrome. METHODS: Gene expression profiles were examined in 17 patients with untreated new-onset systemic JIA, 5 of whom showed evidence of subclinical macrophage...
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