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Article

Type I interferon in rheumatic diseases.

Nature reviews. Rheumatology - 21 Mar 2018

Muskardin Theresa L Wampler, Niewold Timothy B

Abstract excerpt

The type I interferon pathway has been implicated in the pathogenesis of a number of rheumatic diseases, including systemic lupus erythematosus, Sjögren syndrome, myositis, systemic sclerosis, and rheumatoid arthritis. In normal immune responses, type I interferons have a critical role in the defence against viruses, yet in many rheumatic diseases, large subgroups of patients demonstrate persistent activation of...

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Identifiers

PMID: 29559718
DOI: 10.1038/nrrheum.2018.31
PMCID: PMC6625751

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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