Article
The terminal and internal hairpin loops of the ctRNA of plasmid pJB01 play critical roles in regulating copy number.
Molecules and cells - 31 Jul 2008
Kim Sam Woong, Jeong In Sil, Jeong Eun Ju, Tak Je Il, Lee John Hwa, Eo Seong Kug, Kang Ho Young, Bahk Jeong Dong
Abstract excerpt
The plasmid pJB01, a member of the pMV158 family isolated from Enterococcus faecium JC1, contains three open reading frames, copA, repB, and repC. Plasmids included in this family produce counter-transcribed RNA (ctRNA) that contributes to copy number control. The pJB01 ctRNA, a transcript which consists of 54 nucleotides (nts), is encoded on the opposite strand from the copA/repB intergenic region and partially...
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