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DNA-Binding Proteins Regulating pIP501 Transfer and Replication

11 Aug 2016

Abstract excerpt

pIP501 is a Gram-positive broad-host-range model plasmid intensively used for studying plasmid replication and conjugative transfer. It is a multiple antibiotic resistance plasmid frequently detected in clinical Enterococcus faecalis and Enterococcus faecium strains. Replication of pIP501 proceeds unidirectionally by a theta mechanism. The minimal replicon of pIP501 is composed of the repR gene encoding the...

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PMID: 27563645
DOI: 10.3389/fmolb.2016.00042

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