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Article

Molecular dynamics simulations of Alzheimer Abeta40 elongation and lateral association.

Frontiers in bioscience : a journal and virtual library - 1 May 2008

Zheng Jie, Ma Buyong, Chang Yung, Nussinov Ruth

Abstract excerpt

Amyloid-beta (Abeta) peptides can elongate in the fibril axis and associate in the lateral direction. We present detailed atomic Abeta models with different in-register intermolecular beta-sheet-beta-sheet associations. We probe structural stability, conformational dynamics, and association force...

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Identifiers

PMID: 18508486
DOI: 10.2741/2980
PMCID: PMC6413880

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-18508486-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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