Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Loss of heterozygosity, microsatellite instability and TP53 gene status in ovarian carcinomas.

Anticancer research - 1 Jan 2000

Plisiecka-Hałasa Joanna, Dansonka-Mieszkowska Agnieszka, Kraszewska Ewa, Dańska-Bidzińska Anna, Kupryjańczyk Jolanta

Abstract excerpt

BACKGROUND: Microsatellite instability (MSI) and loss of heterozygosity (LOH) are frequent events in ovarian carcinogenesis; however, little is known as to their clinical significance and association with other molecular lesions. MATERIALS AND METHODS: Twelve microsatellite markers for MSI and LOH analysis were used in 64 ovarian carcinomas with known TP53 mutational status. The clinical importance of molecular...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Chromosomes, Human, Pair 17
Share to Genes, p53

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Loss of Heterozygosity

Share to Microsatellite Instability

Share to Microsatellite Repeats

Share to Mutation

Share to Ovarian Neoplasms

Share to Platinum Compounds

Source

Identifiers

PMID: 18507046

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Loss of heterozygosity, microsatellite instability and TP53 gene status in ovarian carcinomas.PMID 18507046Read ↗

Analysis of loss of heterozygosity and KRAS2 mutations in ovarian neoplasms: clinicopathological correlations.Semantic proximity Read ↗

Poor correlation with loss of heterozygosity on chromosome 17p and p53 mutations in ovarian cancers.Semantic proximity Read ↗

Allelic loss at BRCA1, BRCA2, and adjacent loci in relation to TP53 abnormality in breast cancer.Semantic proximity Read ↗

Overexpression of the p53 protein and allele loss at 17p13 in ovarian carcinoma.Semantic proximity Read ↗

Allele loss from large regions of chromosome 17 is common only in certain histological subtypes of ovarian carcinomas.Semantic proximity Read ↗

Molecular genetic changes in human epithelial ovarian malignancies.Semantic proximity Read ↗

p53 mutation in epithelial ovarian carcinoma and borderline ovarian tumor.Semantic proximity Read ↗

Genetic alterations of the tumour suppressor gene regions 3p, 11p, 13q, 17p, and 17q in human breast carcinomas.Semantic proximity Read ↗

Loss of heterozygosity and microsatellite instability as predictive markers for neoadjuvant treatment in gastric carcinoma.Semantic proximity Read ↗

Loss of heterozygosity and genomic instability in synchronous endometrioid tumors of the ovary and endometriumSemantic proximity Read ↗

Patterns of allelic loss on chromosome 17 in sporadic breast carcinomas detected by fluorescent-labeled microsatellite analysis.Semantic proximity Read ↗

Microsatellite DNA alterations of gastrointestinal stromal tumors are predictive for outcome.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.