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Article

Short tail with skin lesion phenotype occurs in transgenic mice with keratin-14 promoter-directed expression of mutant CXCR2.

Journal of leukocyte biology - 1 Aug 2008

Yu Yingchun, Su Yingjun, Opalenik Susan R, Sobolik-Delmaire Tammy, Neel Nicole F, Zaja-Milatovic Snjezana, Short Sarah T, Sai Jiqing, Richmond Ann

Abstract excerpt

CXCR2 plays an important role during cutaneous wound healing. Transgenic mice were generated using the keratin-14 promoter/enhancer to direct expression of wild-type human CXCR2 (K14hCXCR2 WT) or mutant CXCR2, in which the carboxyl-terminal domain (CTD) was truncated at Ser 331 and the dileucine...

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Share to Enhancer Elements, Genetic
Share to Keratin-14
Share to Mice, Mutant Strains

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Mice, Transgenic

Share to Receptors, Interleukin-8B

Share to Sequence Deletion

Source

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Identifiers

PMID: 18505935
DOI: 10.1189/jlb.0807544
PMCID: PMC2493076

Genes

CXCR2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-18505935-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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