Article
Tissue transglutaminase modulates alpha-synuclein oligomerization.
Protein science : a publication of the Protein Society - 1 Aug 2008
Segers-Nolten Ine M J, Wilhelmus Micha M M, Veldhuis Gertjan, van Rooijen Bart D, Drukarch Benjamin, Subramaniam Vinod
Abstract excerpt
We have studied the interaction of the enzyme tissue transglutaminase (tTG), catalyzing cross-link formation between protein-bound glutamine residues and primary amines, with Parkinson's disease-associated alpha-synuclein protein variants at physiologically relevant concentrations. We have, for t...
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