Prevalence of germline MUTYH mutations among Lynch-like syndrome patients.

doi:10.1016/j.ejca.2014.05.022

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Article

Prevalence of germline MUTYH mutations among Lynch-like syndrome patients.

European journal of cancer (Oxford, England : 1990) - 1 Sept 2014

Castillejo Adela, Vargas Gardenia, Castillejo María Isabel, Navarro Matilde, Barberá Víctor Manuel, González Sara, Hernández-Illán Eva, Brunet Joan, Ramón y Cajal Teresa, Balmaña Judith, Oltra Silvestre, Iglesias Sílvia, Velasco Angela, Solanes Ares, Campos Olga, Sánchez Heras Ana Beatriz, Gallego Javier, Carrasco Estela, González Juan Dolors, Segura Angel, Chirivella Isabel, Juan María José, Tena Isabel, Lázaro Conxi, Blanco Ignacio, Pineda Marta, Capellá Gabriel, Soto José Luis

Abstract excerpt

BACKGROUND AND AIMS: Individuals with tumours showing mismatch repair (MMR) deficiency not linked to germline mutations or somatic methylation of MMR genes have been recently referred as having 'Lynch-like syndrome' (LLS). The genetic basis of these LLS cases is unknown. MUTYH-associated polyposis patients show some phenotypic similarities to Lynch syndrome patients. The aim of this study was to investigate the...

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Identifiers

PMID: 24953332
DOI: 10.1016/j.ejca.2014.05.022

Genes

MUTYH
KRAS

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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