Article
Transformation and establishment of fragile X cell lines from amniocytes.
American journal of medical genetics - 1 Jan 2000
Jenkins L S, Gruenert D C, Jenkins E C, Schonberg S A
Abstract excerpt
Fragile X [fra(X)] cell lines have been established from an expressing 46,XX amniocyte culture. The amniocyte cells were transformed by the addition of an origin defective pSV40 vector. Fra(X) expression was observed at a frequency of 3% in the parental amniocyte cell line, and the transformed cl...
Topics
- Amniotic Fluid
- Cell Line, Transformed
- Defective Viruses
- Female
- Fragile X Syndrome
- Humans
- Phenotype
- Prenatal Diagnosis
- Reference Standards
- Simian virus 40