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Article

Transformation and establishment of fragile X cell lines from amniocytes.

American journal of medical genetics - 1 Jan 2000

Jenkins L S, Gruenert D C, Jenkins E C, Schonberg S A

Abstract excerpt

Fragile X [fra(X)] cell lines have been established from an expressing 46,XX amniocyte culture. The amniocyte cells were transformed by the addition of an origin defective pSV40 vector. Fra(X) expression was observed at a frequency of 3% in the parental amniocyte cell line, and the transformed clones expressed the fra(X) site at a frequency of 9-13%. These cell lines maintain the cytogenetic phenotype and can...

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Source

Identifiers

PMID: 1850193
DOI: 10.1002/ajmg.1320380253

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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