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Article

Identification of amino acids essential for estrone-3-sulfate transport within transmembrane domain 2 of organic anion transporting polypeptide 1B1.

PloS one - 1 Jan 2012

Li Nan, Hong Weifang, Huang Hong, Lu Hanping, Lin Guangyun, Hong Mei

Abstract excerpt

As an important structure in membrane proteins, transmembrane domains have been found to be crucial for properly targeting the protein to cell membrane as well as carrying out transport functions in transporters. Computer analysis of OATP sequences revealed transmembrane domain 2 (TM2) is among those transmembrane domains that have high amino acid identities within different family members. In the present study,...

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PMID: 22574206
DOI: 10.1371/journal.pone.0036647
PMCID: PMC3344916

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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