Article
Association between a polymorphism in the IL-12p40 gene and cytomegalovirus reactivation after kidney transplantation.
Transplantation - 27 May 2008
Hoffmann Thomas W, Halimi Jean-Michel, Büchler Mathias, Velge-Roussel Florence, Goudeau Alain, Al Najjar Azmi, Boulanger Marie-Denise, Houssaini Tarik Sqalli, Marliere Jean-Frédéric, Lebranchu Yvon, Baron Christophe
Abstract excerpt
BACKGROUND: Cytomegalovirus (CMV) infection is associated with a significant rate of morbidity after organ transplantation. The genetic factors influencing its occurrence have been little investigated. IL-12 plays a crucial role in anti-infectious immune responses, especially by stimulating IFNga...
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