Article
[Relationship between PAI-1 gene 4G/5G polymorphism and clinical profile of IgA nephropathy].
Zhonghua yi xue yi chuan xue za zhi = Zhonghua yixue yichuanxue zazhi = Chinese journal of medical genetics - 1 Aug 2006
Ding Rui, Chen Xiang-mei, Liu Shu-wen, Lv Yang, Wu Jie
Abstract excerpt
OBJECTIVE: It is clear that PAI-1 is a very important factor inhibiting extracellular matrix (ECM) degradation in the pathology process of IgA nephropathy (IgAN), so we design to investigate the relationship between PAI-1 promoter 4G/5G polymorphism and IgAN pathogenesis and progression. METHODS: Clinical baseline data such as blood pressure, urinary protein excretion, serum profile, and extent of renal tissue...
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