Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Gestational all-trans retinoic acid treatment in the rat: neurofunctional changes and cerebellar phenotype.

Neurotoxicology and teratology - 1 Jan 2000

Coluccia Addolorata, Belfiore Domenico, Bizzoca Antonella, Borracci Pietro, Trerotoli Paolo, Gennarini Gianfranco, Carratù Maria Rosaria

Abstract excerpt

Neurofunctional effects produced by gestational all-trans retinoic acid (all-trans RA) treatment were investigated in the offspring of Sprague-Dawley rats. Reproduction data, onset of reflexive behavior, locomotor activity, motor coordination and motor learning were examined. Moreover, possible changes in size and morphology of the cerebellum were evaluated. The results show that all-trans RA treatment (2.5...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Dyskinesia, Drug-Induced
Share to Learning Disabilities

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Nervous System Malformations

Share to Neural Pathways

Share to Stereoisomerism

Share to Teratogens

Share to Tretinoin

Source

Identifiers

PMID: 18495421
DOI: 10.1016/j.ntt.2008.03.064

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Gestational all-trans retinoic acid treatment in the rat: neurofunctional changes and cerebellar phenotype.PMID 18495421Read ↗

The neurobehavioral teratology of retinoids: A 50‐year historySemantic proximity Read ↗

Preventive effects of resveratrol against early-life impairments in the animal model of autism induced by valproic acidSemantic proximity Read ↗

13-cis-retinoic acid causes patterning defects in the early embryonic rostral hindbrain and abnormal development of the cerebellum in the macaque.Semantic proximity Read ↗

Impaired structural and functional development of cerebellum following gestational exposure of deltamethrin in rats: role of reelin.Semantic proximity Read ↗

Retinoids as TeratogensSemantic proximity Read ↗

RORalpha, a pivotal nuclear receptor for Purkinje neuron survival and differentiation: from development to ageing.Semantic proximity Read ↗

Active maternal phenotype is established before breeding and leads offspring to align growth trajectory outcomes and reflex ontogeny.Semantic proximity Read ↗

Thyroid hormone receptor beta mutation causes severe impairment of cerebellar development.Semantic proximity Read ↗

Alteration of cerebellar neurotropin messenger ribonucleic acids and the lack of thyroid hormone receptor augmentation by staggerer-type retinoic acid receptor-related orphan receptor-alpha mutation.Semantic proximity Read ↗

Hypothesis: Prenatal Ethanol‐Induced Birth Defects and Retinoic AcidSemantic proximity Read ↗

Divergent pattern of development in rats and humansSemantic proximity Read ↗

Effects of all-trans-retinoic acid on limb development in the genetic polydactyly mouse.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.