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Article

Hypothesis: Prenatal Ethanol‐Induced Birth Defects and Retinoic Acid

1 Jun 1991

Abstract excerpt

A hypothesis is presented to explain the biochemical basis of ethanol-induced birth defects. Prenatal ethanol exposure causes central nervous system and limb abnormalities in humans and in animals. Retinoic acid and didehydroretinoic acid are known to play an important role in the central nervous system and limb developments. Ethanol is known to inhibit the formation of retinoic acid from retinol and deplete...

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Identifiers

PMID: 1877745
DOI: 10.1111/j.1530-0277.1991.tb00561.x

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