Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Glutathione S-transferase enzyme polymorphisms in a Hungarian myelodysplasia study population.

Pathology oncology research : POR - 1 Dec 2008

Várkonyi Judit, Szakály Dóra, Jánoskúti Lívia, Hosszúfalusi Nóra, Pánczél Pál, Karádi István, Schoket Bernadette

Abstract excerpt

GSTM1, GSTT1 and GSTP1 Ile105Val that are members of the GST gene family encode for Phase II drug/xenobiotic metabolizing enzymes, primarily with detoxifying function, and are polymorphic in humans. GSTM1 and GSTT1 homozygous deletion genotypes do not express the enzymes. It has been hypothesised that individuals with homozygous deletion of the GSTM1 and/or GSTT1 gene may have lower detoxification capacity...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Aged, 80 and over
Share to Case-Control Studies

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Glutathione Transferase

Share to Hungary

Share to Myelodysplastic Syndromes

Share to Polymerase Chain Reaction

Share to Polymorphism, Genetic

Share to Risk Factors

Source

Identifiers

PMID: 18493876
DOI: 10.1007/s12253-008-9008-1

Genes

GSTM1
GSTT1
GSTP1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Glutathione S-transferase enzyme polymorphisms in a Hungarian myelodysplasia study population.PMID 18493876Read ↗

Polymorphisms of detoxification and DNA repair enzymes in myelodyplastic syndromes.Semantic proximity Read ↗

Association of A(313)G glutathione S-transferase P1 germline polymorphism with susceptibility to de novo myelodysplastic syndrome.Semantic proximity Read ↗

Polymorphism in glutathione S-transferase P1 is associated with susceptibility to chemotherapy-induced leukemia.Semantic proximity Read ↗

Increased risk for myelodysplastic syndromes in individuals with glutathione transferase theta 1 (GSTT1) gene defect.Semantic proximity Read ↗

Increased prevalence of GSTM(1) null genotype in patients with myelodysplastic syndrome: a case-control study.Semantic proximity Read ↗

Gluthatione-S-transferase T1-null genotype predisposes adults to acute promyelocytic leukemia; a case-control study.Semantic proximity Read ↗

Glutathione S-transferase polymorphisms in children with myeloid leukemia: a Children's Cancer Group study.Semantic proximity Read ↗

Genotype of glutathione S-transferase and other genetic configurations in myelodysplasia.Semantic proximity Read ↗

Glutathione S-transferase theta 1 gene deletion and risk of acute myeloid leukemia.Semantic proximity Read ↗

Human glutathione S-transferase GSTM1 genetic polymorphism in Estonia.Semantic proximity Read ↗

Glutathione S-transferase polymorphisms and susceptibility to neuroblastoma.Semantic proximity Read ↗

Association of GSTM1, GSTT1 and GSTP1 Ile105Val polymorphisms with clinical response to imatinib mesylate treatment among Malaysian chronic myeloid leukaemia patients.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.