Article
Mapping of quantitative trait loci affecting classical scrapie incubation time in a population comprising several generations of scrapie-infected sheep.
The Journal of general virology - 1 Feb 2010
Moreno Carole R, Moazami-Goudarzi Katayoun, Briand Stephanie, Robert-Granié Christèle, Weisbecker Jean Louis, Laurent Pascal, Cribiu Edmond-Paul, Haley Christopher S, Andréoletti Olivier, Bishop Stephen C, Pong-Wong Ricardo
Abstract excerpt
Although susceptibility to scrapie is largely controlled by the PrP gene, the role of other genes that affect scrapie resistance in sheep is now confirmed. Following the detection of quantitative trait loci (QTL) on chromosomes 6 and 18 in a half-sib family with an ARQ/VRQ susceptible PrP genotype, the whole pedigree of a naturally infected flock was investigated to confirm these QTL regions in different PrP...
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