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Article

Retinoids upregulate phosphoenolpyruvate carboxykinase and glyceroneogenesis in human and rodent adipocytes.

The Journal of nutrition - 1 Jun 2008

Cadoudal Thomas, Glorian Martine, Massias Aurélie, Fouque Françoise, Forest Claude, Benelli Chantal

Abstract excerpt

Glyceroneogenesis is an important metabolic pathway for fatty acid reesterification in adipose tissue, thereby reducing fatty acid release. Glyceroneogenesis and cytosolic phosphoenolpyruvate carboxykinase (PEPCK-C), which is the key enzyme in this pathway, are both regulated by a series of hormones and nutrients, among which all-trans retinoic acid (all-trans RA) is a transcriptional inducer of the PEPCK-C gene...

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Source

Identifiers

PMID: 18492826
DOI: 10.1093/jn/138.6.1004

Genes

PCK1
PCK2

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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