Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Peroxisome proliferator-activated receptor γ-dependent regulation of lipolytic nodes and metabolic flexibility.

Molecular and cellular biology - 1 Apr 2012

Rodriguez-Cuenca Sergio, Carobbio Stefania, Velagapudi Vidya R, Barbarroja Nuria, Moreno-Navarrete Jose Maria, Tinahones Francisco Jose, Fernandez-Real Jose Manuel, Orešic Matej, Vidal-Puig Antonio

Abstract excerpt

Optimal lipid storage and mobilization are essential for efficient adipose tissue. Nuclear receptor peroxisome proliferator-activated receptor γ (PPARγ) regulates adipocyte differentiation and lipid deposition, but its role in lipolysis and dysregulation in obesity is not well defined. This investigation aimed to understand the molecular impact of dysfunctional PPARγ on the lipolytic axis and to explore whether...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Catecholamines
Share to Cyclic AMP-Dependent Protein Kinases

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Leptin

Share to Lipolysis

Share to Obesity

Share to PPAR gamma

Share to Signal Transduction

Source

Open in PubMed Open full text

Identifiers

PMID: 22310664
DOI: 10.1128/MCB.06154-11
PMCID: PMC3318581

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Peroxisome proliferator-activated receptor γ-dependent regulation of lipolytic nodes and metabolic flexibility.PMID 22310664Read ↗

PPARs and Metabolic Disorders Associated with Challenged Adipose Tissue PlasticitySemantic proximity Read ↗

Mouse models of PPAR-γ deficiency: dissecting PPAR-γ's role in metabolic homoeostasisSemantic proximity Read ↗

Peroxisome Proliferator-Activated Receptor γ in White and Brown Adipocyte Regulation and DifferentiationSemantic proximity Read ↗

Thematic Review Series: Glycerolipids. Multiple roles for lipins/phosphatidate phosphatase enzymes in lipid metabolism.Semantic proximity Read ↗

Understanding the variegation of fat: Novel regulators of adipocyte differentiation and fat tissue biologySemantic proximity Read ↗

VLDL hydrolysis by hepatic lipase regulates PPARδ transcriptional responses.Semantic proximity Read ↗

PPARγ mutations, lipodystrophy and diabetes.Semantic proximity Read ↗

Familial partial lipodystrophy resulting from loss-of-function PPARγ pathogenic variants: phenotypic, clinical, and genetic features.Semantic proximity Read ↗

Peroxisome Proliferator-Activated Receptor-γ: Master Regulator of Adipogenesis and ObesitySemantic proximity Read ↗

PPARgamma in human and mouse physiology.Semantic proximity Read ↗

Leptin Deficiency Unmasks the Deleterious Effects of Impaired Peroxisome Proliferator–Activated Receptor γ Function (P465L PPARγ) in MiceSemantic proximity Read ↗

Peroxisome proliferator-activated receptor gamma (PPARgamma) and its ligands: a review.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.