Article
Combined genotype analysis of GSTM1 and GSTT1 polymorphisms in a Polish population.
Human biology - 1 Apr 2003
Kargas Christos, Krupa Renata, Walter Zofia
Abstract excerpt
This study describes the distribution of GSTT1 and GSTM1 polymorphisms in a normal population of central Poland. A homozygous inherited deletion of either gene leads to absence of enzyme activity in affected individuals, and those lacking more than one detoxifying gene are at the highest risk for diseases caused by environmental factors. The prevalence of the "null" genotype of the GSTM1 and GSTT1 genes was...
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