Article
Normal sleep homeostasis and lack of epilepsy phenotype in GABA A receptor alpha3 subunit-knockout mice.
Neuroscience - 23 Jun 2008
Winsky-Sommerer R, Knapman A, Fedele D E, Schofield C M, Vyazovskiy V V, Rudolph U, Huguenard J R, Fritschy J-M, Tobler I
Abstract excerpt
Thalamo-cortical networks generate specific patterns of oscillations during distinct vigilance states and epilepsy, well characterized by electroencephalography (EEG). Oscillations depend on recurrent synaptic loops, which are controlled by GABAergic transmission. In particular, GABA A receptors...
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