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Article

Normal sleep homeostasis and lack of epilepsy phenotype in GABA A receptor alpha3 subunit-knockout mice.

Neuroscience - 23 Jun 2008

Winsky-Sommerer R, Knapman A, Fedele D E, Schofield C M, Vyazovskiy V V, Rudolph U, Huguenard J R, Fritschy J-M, Tobler I

Abstract excerpt

Thalamo-cortical networks generate specific patterns of oscillations during distinct vigilance states and epilepsy, well characterized by electroencephalography (EEG). Oscillations depend on recurrent synaptic loops, which are controlled by GABAergic transmission. In particular, GABA A receptors containing the alpha3 subunit are expressed predominantly in cortical layer VI and thalamic reticular nucleus (nRT) and...

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Identifiers

PMID: 18485607
DOI: 10.1016/j.neuroscience.2008.03.081
PMCID: PMC2587445

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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