Article
The influence of surface mineral and osteopontin on the formation and function of murine bone marrow-derived osteoclasts.
Journal of materials science. Materials in medicine - 1 Oct 2008
Rajachar Rupak M, Truong Anh Q, Giachelli Cecilia M
Abstract excerpt
The phosphorylated glycoprotein osteopontin (OPN) is involved in the regulation of biomineralization under normal and pathological conditions. Its actions include inhibiting apatite crystal growth and promoting the formation and function of mineral resorbing cells, including osteoclasts (OCL). The purpose of this study was to develop stable apatitic mineral surfaces and determine their influence on OCL formation...
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