Article
Hormone receptor-related gene polymorphisms and prostate cancer risk in North Indian population.
Molecular and cellular biochemistry - 1 Jul 2008
Onsory Khadijeh, Sobti R C, Al-Badran Adnan Issa, Watanabe Masatoshi, Shiraishi Taizo, Krishan Awtar, Mohan Harsh, Kaur Pushpinder
Abstract excerpt
The purpose of this study was to analyse the frequency and type of mutations in the coding region of androgen receptor (AR) and to determine the role of polymorphisms in the intron 1 of ERalpha, exon 5 of ERbeta, intron 7 of progesterone, exon 7 of the aromatase (CYP19) and exon 9 of VDR genes in the risk of prostate cancer. PCR-RFLP analysis of all above the genes was on 100 prostate cancer patients and an equal...
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