Article
Allelic variants of aromatase and the androgen and estrogen receptors: toward a multigenic model of prostate cancer risk.
Clinical cancer research : an official journal of the American Association for Cancer Research - 1 Oct 2001
Modugno F, Weissfeld J L, Trump D L, Zmuda J M, Shea P, Cauley J A, Ferrell R E
Abstract excerpt
PURPOSE: The purpose of this study was to determine whether polymorphisms in the CAG repeat in exon 1 of the androgen receptor (AR), two intronic restriction sites in the estrogen receptor (ESR1 XbaI and ESR1 PvuII), and an Arg264Cy5 substitution in the aromatase gene (CYP19) contribute to prostate cancer risk. EXPERIMENTAL DESIGN: A case-control study was performed with 88 Caucasian prostate cancer patients and...
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