Article
The -30G>A polymorphism of the glucokinase gene promoter is associated with obesity in a population from southern Spain.
Obesity (Silver Spring, Md.) - 1 Aug 2008
Gómez-Zumaquero Juan M, Rojo-Martínez G, García-Escobar E, Martín-Nuñez Gracia M, Haro J, Esteva I, Ruiz de Adana M, Cuesta Antonio L, Olveira G, Morcillo S, Soriguer F
Abstract excerpt
The aim of this study was to test the hypothesis of an association between the -30G>A polymorphism of the promoter of the glucokinase gene and the prevalence and incidence of obesity. We studied the -30G>A polymorphism of the glucokinase gene promoter in 981 persons, of whom 866 were seen again 6 years later. All the persons underwent an oral glucose-tolerance test and the BMI (weight/height(2)) was recorded. The...
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