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Article

A new variation in the promoter region, the -604 C>T, and the Leu72Met polymorphism of the ghrelin gene are associated with protection to insulin resistance.

International journal of obesity (2005) - 1 Apr 2008

Zavarella S, Petrone A, Zampetti S, Gueorguiev M, Spoletini M, Mein C A, Leto G, Korbonits M, Buzzetti R

Abstract excerpt

OBJECTIVE: Previous studies suggested that polymorphisms in the coding region of the preproghrelin were involved in the etiology of obesity and might modulate glucose-induced insulin secretion. We evaluated the association of a new variation, -604C>T, in the promoter region of the ghrelin gene, o...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 18071345
DOI: 10.1038/sj.ijo.0803766

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-18071345-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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A new variation in the promoter region, the -604 C>T, and the Leu72Met polymorphism of the ghrelin gene are associated with protection to insulin resistance.PMID 18071345Read ↗

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Association of A-604G ghrelin gene polymorphism and serum ghrelin levels with the risk of obesity in a mexican population.Semantic proximity Read ↗

Association between ghrelin gene variations and blood pressure in subjects with impaired glucose tolerance.Semantic proximity Read ↗

Molecular screening of the ghrelin gene in Italian obese children: the Leu72Met variant is associated with an earlier onset of obesity.Semantic proximity Read ↗

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The Leu72Met polymorphism of the ghrelin gene is associated with a decreased risk for type 2 diabetes.Semantic proximity Read ↗

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