Article
Complete genome sequence of Treponema pallidum ssp. pallidum strain SS14 determined with oligonucleotide arrays.
BMC microbiology - 15 May 2008
Matejková Petra, Strouhal Michal, Smajs David, Norris Steven J, Palzkill Timothy, Petrosino Joseph F, Sodergren Erica, Norton Jason E, Singh Jaz, Richmond Todd A, Molla Michael N, Albert Thomas J, Weinstock George M
Abstract excerpt
BACKGROUND: Syphilis spirochete Treponema pallidum ssp. pallidum remains the enigmatic pathogen, since no virulence factors have been identified and the pathogenesis of the disease is poorly understood. Increasing rates of new syphilis cases per year have been observed recently. RESULTS: The genome of the SS14 strain was sequenced to high accuracy by an oligonucleotide array strategy requiring hybridization to...
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