Article
Syphilis-causing strains belong to separate SS14-like or Nichols-like groups as defined by multilocus analysis of 19 Treponema pallidum strains.
International journal of medical microbiology : IJMM - 1 Jul 2014
Nechvátal Lukáš, Pětrošová Helena, Grillová Linda, Pospíšilová Petra, Mikalová Lenka, Strnadel Radim, Kuklová Ivana, Kojanová Martina, Kreidlová Miluše, Vaňousová Daniela, Procházka Přemysl, Zákoucká Hana, Krchňáková Alena, Smajs David
Abstract excerpt
Treponema pallidum strains are closely related at the genome level but cause distinct diseases. Subspecies pallidum (TPA) is the causative agent of syphilis, subspecies pertenue (TPE) causes yaws while subspecies endemicum (TEN) causes bejel (endemic syphilis). Compared to the majority of treponemal genomic regions, several chromosomal loci were found to be more diverse. To assess genetic variability in diverse...
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