Origin of modern syphilis and emergence of a pandemic Treponema pallidum cluster.

doi:10.1038/nmicrobiol.2016.245

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Article

Origin of modern syphilis and emergence of a pandemic Treponema pallidum cluster.

Nature microbiology - 5 Dec 2016

Arora Natasha, Schuenemann Verena J, Jäger Günter, Peltzer Alexander, Seitz Alexander, Herbig Alexander, Strouhal Michal, Grillová Linda, Sánchez-Busó Leonor, Kühnert Denise, Bos Kirsten I, Davis Leyla Rivero, Mikalová Lenka, Bruisten Sylvia, Komericki Peter, French Patrick, Grant Paul R, Pando María A, Vaulet Lucía Gallo, Fermepin Marcelo Rodríguez, Martinez Antonio, Centurion Lara Arturo, Giacani Lorenzo, Norris Steven J, Šmajs David, Bosshard Philipp P, González-Candelas Fernando, Nieselt Kay, Krause Johannes, Bagheri Homayoun C

Abstract excerpt

The abrupt onslaught of the syphilis pandemic that started in the late fifteenth century established this devastating infectious disease as one of the most feared in human history1. Surprisingly, despite the availability of effective antibiotic treatment since the mid-twentieth century, this bacterial infection, which is caused by Treponema pallidum subsp. pallidum (TPA), has been re-emerging globally in the last...

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PMID: 27918528
DOI: 10.1038/nmicrobiol.2016.245

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