Article
Investigation of the functional brain-derived neurotrophic factor gene variant Val66MET in migraine.
Journal of neural transmission (Vienna, Austria : 1996) - 1 Sept 2008
Marziniak Martin, Herzog Anna Laura, Herzog Andrea, Mössner Rainald, Sommer Claudia
Abstract excerpt
Experimental studies and investigations of the cerebrospinal fluid in migraineurs have suggested an involvement of brain-derived neurotrophic factor (BDNF) in migraine pathophysiology. In a case-control study approach, the functional Val66MET polymorphism (rs6265) of the BDNF gene was investigated in 265 migraine patients and 153 controls. Genotype and allele frequencies did not differ between healthy subjects...
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