Article
Association analysis of brain-derived neurotrophic factor (BDNF) gene Val66Met polymorphism in schizophrenia and bipolar affective disorder.
The world journal of biological psychiatry : the official journal of the World Federation of Societies of Biological Psychiatry - 1 Oct 2004
Skibinska Maria, Hauser Joanna, Czerski Piotr M, Leszczynska-Rodziewicz Anna, Kosmowska Magdalena, Kapelski Pawel, Slopien Agnieszka, Zakrzewska Marzena, Rybakowski Janusz K
Abstract excerpt
Brain-derived neurotrophic factor (BDNF) has been implicated in the pathogenesis of schizophrenia and bipolar disorder. A functional polymorphism Val66Met of BDNF gene was studied in patients with schizophrenia (n=336), bipolar affective disorder (n=352) and healthy controls (n=375). Consensus diagnosis by at least two psychiatrists, according to DSM-IV and ICD-10 criteria, was made for each patient using a...
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