Article
Addictions biology: haplotype-based analysis for 130 candidate genes on a single array.
Alcohol and alcoholism (Oxford, Oxfordshire) - 1 Jan 2000
Hodgkinson Colin A, Yuan Qiaoping, Xu Ke, Shen Pei-Hong, Heinz Elizabeth, Lobos Elizabeth A, Binder Elizabeth B, Cubells Joe, Ehlers Cindy L, Gelernter Joel, Mann John, Riley Brien, Roy Alec, Tabakoff Boris, Todd Richard D, Zhou Zhifeng, Goldman David
Abstract excerpt
AIMS: To develop a panel of markers able to extract full haplotype information for candidate genes in alcoholism, other addictions and disorders of mood and anxiety. METHODS: A total of 130 genes were haplotype tagged and genotyped in 7 case/control populations and 51 reference populations using Illumina GoldenGate SNP genotyping technology, determining haplotype coverage. We also constructed and determined the...
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